Publications

See below for details of recent publications:

 

 International Development Committee written evidence submitted by Dr Geoff Coxon, TBD-UK

(14th Department for International Development Annual Report, published 9 March 2012

 

Strategies and Challenges Involved in the Discovery of New Chemical Entities During Early-Stage Tuberculosis Drug Discovery 

(Published in Journal of Infectious Diseases, 23rd March 2012)

 

Innovative Trial Designs Are Practical Solutions for Improving the Treatment of Tuberculosis

(Published in Journal of Infectious Diseases, 23rd March 2012)

 

 Essential residues for the enzyme activity of ATP-dependent MurE ligase from Mycobacterium tuberculosis

(Published in Protein & Cell 1(11), 1011-1022, November 2010)

 

Anti-tubercular screening of natural products from Colombian plants: 3-methoxynordomesticine, an inhibitor of MurE ligase of Mycobacterium tuberculosis

(Published in Journal of Antimicrobial Chemotherapy, 18th August 2010)

 

Comparison of the Moonlighting Actions of the Two Highly Homologous Chaperonin 60 Proteins of Mycobacterium tuberculosis

(Published in Infection and Immunity, April 2010)

 

Multiple moonlighting functions of mycobacterial molecular chaperones

(Published in Tuberculosis, March 2010)

 

3-Ketosteroid 9a-hydroxylase is an essential factor in the pathogenesis of Mycobacterium tuberculosis

(Published in Molecular Microbiology, January 2010)

 

Thioridazine cures extensively drug-resistant tuberculosis (XDR-TB) and the need for global trials is now

(Published in International Journal of Antimicrobial Agents, 25th February 2010)

 

TB - Strength in numbers  

(Published in SGM Microbiology Today, 12th February 2010)

 

Identification of arylamine N-acetyltransferase inhibitors as an approach towards novel anti-tuberculars

(Published in Protein and Cell, 6th February 2010)

 

ATP-dependent MurE ligase in Mycobacterium tuberculosis: Biochemical and structural characterisation

(Published in Tuberculosis, January 2010)

  

Fast-growing, non-infectious and intracellularly surviving drug-resistant Mycobacterium aurum: a model for high-throughput antituberculosis drug screening

(Published in Journal of Antimicrobial Chemotherapy, 4th August 2009)

 

Identification of 2-Aminothiazole-4-Carboxylate Derivatives Active against Mycobacterium tuberculosis   

(Published in PLoS one, 19th May 2009)

 

Acute and Persistent Mycobacterium tuberculosis Infections Depend on the Thiol Peroxidase TPX

(Published in PLoS one, April 2009)

 

Antibiotic Resistance Protocols Second Edition

(Published 1st April 2009)

 

The two homologous chaperonin 60 proteins of Mycobacterium tuberculosis have distinct effects on monocyte differentiation into osteoclasts

(Published in Cellular Microbiology, October 2008)